Professional Experience:

6/85-8/86 Lab Assistant II, Department of Biology, University of California, San Diego

10/90-8/94 Postdoctoral Fellow, Department of Biology, University of California, Los Angeles

8/94- present Assistant Professor, Department of Microbiology and Immunology, College of Medicine, University of South Alabama

Honors and Awards: President’s Undergraduate Fellowship, University of California, San Diego (1984) National Institutes of Health Predoctoral Training Grant (1986-88) National Institutes of Health Postdoctoral Fellowship (1991-94)

Publications:

1. Dean, D. A., J. D. Fikes, K. Gehring, P. J. Bassford Jr., and H. Nikaido. 1989. Active transport of maltose in membrane vesicles obtained from Escherichia coli cells producing tethered maltose-binding protein. J. Bacteriol. 171: 503-510.

2. Dean, D. A., A. L. Davidson, and H. Nikaido. 1989. Maltose transport in membrane vesicles of Escherichia coli is linked to ATP hydrolysis. Proc. Natl. Acad. Sci. U. S. A. 86: 9134-9138.

3. Dean, D. A., A. L. Davidson, and H. Nikaido. 1990. The role of ATP as the energy source for maltose transport in Escherichia coli. Res. Microbiol. 141: 348-352.

4. Dean, D. A., J. Reizer, H. Nikaido, and M. H. Saier Jr. 1990. Regulation of the maltose transport system of Escherichia coli by the glucose-specific enzyme III of the phosphoenolpyruvate-sugar phosphotransferase system. Characterization of inducer exclusion-resistant mutants and reconstitution of inducer exclusion in proteoliposomes. J. Biol. Chem. 265:21005-21010.

5. Dean, D. A., L. I. Hor, H. A. Shuman, and H. Nikaido. 1992. Interaction between maltose-binding protein and the membrane-associated maltose transporter complex in Escherichia coli. Mol. Microbiol. 6: 2033-2040, and Mol. Microbiol.

6: 3627. 6. Clever, J. L., D. A. Dean, and H. Kasamatsu. 1993. Identification of a DNA-binding domain within the simian virus 40 capsid proteins Vp2 and Vp3. J. Biol. Chem. 268: 20877-20883.

7. Dean, D. A. and H. Kasamatsu. 1994. Signal- and energy-dependent nuclear transport of SV40 Vp3 by isolated nuclei. Establishment of a filtration assay for nuclear protein import. J. Biol. Chem. 269: 4910-4916.

8. Dean, D. A., P. L. Li, L. M. Lee, and H. Kasamatsu. 1995. Essential role of the Vp2 and Vp3 DNA-binding domain in SV40 morphogenesis. J. Virol. 69: 1115-1121.

9. Dean, D. A. 1997 Import of plasmid DNA into the nucleus is sequence-specific. Exp. Cell Res. 230: 293-302

10. Tran, M. T., D. A. Dean, R. N. Lausch, R. E. Honkanen, and J. E. Oakes. 1997. HSV-1 infection of human corneal epithelial cells does not induce release of intracellular stores of IL-1a. Invest. Ophthalmol. Vis. Sci. 38: S874.

11. Dean, D. A., and T. D. Sherman. 1997. Transport of Plasmid DNA into the nuclei of Tradescantia leaf epidermal cells. Plant Physiol. 114:306.

12. Dean, D. A. 1997. Molecule and method for importing DNA into a nucleus. U.S. Patent.

13. Dean, D. A. 1997. Molecule and method for importing DNA into a nucleus. International patent application No. PCT/US97/05073

14. Dean, D. A., and W. E. Zimmer. 1997. Cell-specific molecule and method for importing DNA into a nucleus. U.S. Patent application.

15. Tran, M. T., D. A. Dean, R. N. Lausch, and J. E. Oakes. 1998. Membranes of herpes simplex virus type-1-infected human corneal epithelial cells are not permeabilized to macromolecules and therefore do not release IL-1a. Virology 244:74-78.

16. Dean, D. A., and B. S. Dean. 1998. Nuclear targeting of plasmid DNA in human corneal cells. Cur. Eye Res. (in press).

17. Dean, D. A., M. Sawdey, and B. S. Dean. 1998. Sequence requirements for plasmid DNA nuclear import. (in preparation).

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